Saturday, April 18, 2015

Aniracetam use and effects

Aniracetam is in the racetam chemical class and is more specifically called an AMPAkine.  It is more commonly known as a nootropic drug, so if you want to search the vast variety of natural and synthetic chemicals that can improve brain function, that will help.  Aniracetam is considered chemically similar to piracetam, but if you compare them, they primarily share the 2-pyrrolidin parent chemical, but have different effects and potency.  Aniracetam is many times more potent than piracetam and slightly more potent than oxiracetam.  Don't be confused by the potency differences, just because aniracetam is more potent doesn't mean it's a good fit for you.  The biggest reason I chose to stick with aniracetam is because of it's lower profile of stimulation, but perhaps you would prefer a more stimulating one.

How it is believed to work:
It can affect dopamine, nicotinic acetycholine, serotonin, and AMPA receptors.  It is thought that aniracetam has anti-anxiety, anti-depressant, and memory enhancing effects.  It is argued that its mode of action is preferential modulation of certain receptors, but is conversely argued that it primarily stimulates activity at these receptors.  It has the potential of replenishing the brain of certain neurotransmitters, but is this an "across the board" increase of neurotransmitters or a more regulatory increase?

Personal notes on effects and dosing(aniracetam):
-Increased memory
-Increased thinking speed
-Better reaction time
-Some mood elevation
-Some anxiety relief
-A slight increase in reasoning

I started at a very low dose, because when I first acquired it, there was little information about how stimulating it would be (if you've ever been over-stimulated, you would know why I was so careful).
-Initial daily dosage: 150mg.  Dose tested for 2 weeks with almost no change.
-Increase of daily dosage to 300mg.  As before, 2 weeks of very little change.
-Aniracetam abandoned.

Upon researching the drug class again, I found better information about proper dosages and dose frequency.
-700mg, 1X/day for 1 week.  Noticed that recall was easier by the end of the week.
-700mg, 2X/day for unknown number of weeks(basically stuck with this daily amount).
With settling with 1400mg/day (some suggest taking 2100mg/day), I noticed the effects I listed above.  You need to be patient with this chemical, though some effects are noticed fairly quickly, others take time and you might not even notice the change until something happens (ie- I didn't notice an effect on my reaction time until I was consistently catching things I would have ordinarily fumbled).

I tested an additional theory out: would the benefits remain even after ceasing administration of aniracetam?  Because I didn't perform any definitive tests to verify it, it should be seen as anecdotal also, but 1-2 month administrations of aniracetam seemed to have lasting effects for months that diminished differently based on the effect.  I only tried this twice because I prefer to take it continuously.

Dosing might be different for you, you might need more, you might need less, you might even have a VERY different reaction, so be wise and start low.  There are some natural alternatives to racetam drugs, but they are by no means as effective.  These findings on the effects of aniracetam are based purely on personal observations.

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